Two studies contain shown a impressive confederation between night-time symptoms and the austerity of airflow hurdle in patients with COPD; 19, 20 however, our contemplate was in accordance with the about of Miravittles et al , 13 showing that the frequency of night-time symptoms was comparable across all severities of airflow limitation. The responsibility of physical activity (Sallis and Carlson, pages 169-184) and smoking mutual choices (Abrams and colleagues, pages 143-16

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